Over het archief
Het OWA, het open archief van het Waterbouwkundig Laboratorium heeft tot doel alle vrij toegankelijke onderzoeksresultaten van dit instituut in digitale vorm aan te bieden. Op die manier wil het de zichtbaarheid, verspreiding en gebruik van deze onderzoeksresultaten, alsook de wetenschappelijke communicatie maximaal bevorderen.
Dit archief wordt uitgebouwd en beheerd volgens de principes van de Open Access Movement, en het daaruit ontstane Open Archives Initiative.
Basisinformatie over ‘Open Access to scholarly information'.
| one publication added to basket [323275] |
Erysipelas vaccination protocols in dolphins Tursiops truncatus evaluated by antibody responses over twenty continuous years
Lacave, G.; Cui, Y.; Salbany, A.; Flanagan, C.; Grande, F.; Cox, E. (2019). Erysipelas vaccination protocols in dolphins Tursiops truncatus evaluated by antibody responses over twenty continuous years. Dis. Aquat. Org. 134(3): 237-255. https://dx.doi.org/10.3354/dao03367
In: Diseases of Aquatic Organisms. Inter Research: Oldendorf/Luhe. ISSN 0177-5103; e-ISSN 1616-1580, meer
|  |
| Trefwoorden |
Erysipelothrix rhusiopathiae; Tursiops truncatus (Montagu, 1821) [WoRMS]
Marien/Kust |
| Author keywords |
Bottlenose dolphin; Vaccination; Erysipelothrix rhusiopathiae;Erysipelas; Tursiops truncatus |
| Auteurs | | Top |
- Lacave, G.
- Cui, Y., meer
- Salbany, A.
|
- Flanagan, C.
- Grande, F.
- Cox, E., meer
|
|
| Abstract |
Erysipelas is an infection caused by Erysipelothrix rhusiopathiae that affects many different species around the world, including cetaceans. The acute septicemic form can rapidly cause death in bottlenose dolphins Tursiops truncatus. The ultimate goals of this long-term study were the development and identification of the most effective vaccination protocol against clinical erysipelas in T. truncatus using a commercially available swine vaccine, and to determine whether there is a need for a semi-annual vaccination versus an annual vaccination. The present study concentrated on the immunization of a dolphin population (7 wild-born and 22 captive-born individuals) with 2 swine vaccines, the European ‘Eurovac Ery®’ vaccine and the American ‘ER Bac Plus®’ vaccine, and immunological profile results over a 20-yr time period. The general protocol was a primo-vaccination (between 3 and 7 mo of age for calves) with or without a booster 1 mo post primo-vaccination and either annual or semi-annual vaccination thereafter. Sera were collected prior to vaccination, 2 wk post-vaccination and monthly. A dolphin-specific ELISA was developed to analyze the erysipelas-specific antibody response of vaccinated animals. The final ELISA results (n = 1362 samples from 29 animals at pre- and post-vaccination time) suggest that (1) there is a significant difference in antibody levels at the start of the vaccination between older and younger animals; (2) at least 3 vaccinations are necessary to obtain antibody levels above the levels at pre-vaccination; (3) thereafter, annual vaccinations seem sufficient to keep antibody levels above the levels at pre-vaccination; and (4) both vaccines induced similar responses. No case of erysipelas infection was observed in this population during the study. |
IMIS is ontwikkeld en wordt gehost door het VLIZ.
