Over het archief
Het OWA, het open archief van het Waterbouwkundig Laboratorium heeft tot doel alle vrij toegankelijke onderzoeksresultaten van dit instituut in digitale vorm aan te bieden. Op die manier wil het de zichtbaarheid, verspreiding en gebruik van deze onderzoeksresultaten, alsook de wetenschappelijke communicatie maximaal bevorderen.
Dit archief wordt uitgebouwd en beheerd volgens de principes van de Open Access Movement, en het daaruit ontstane Open Archives Initiative.
Basisinformatie over ‘Open Access to scholarly information'.
Effect of crude oil contaminated sediment exposure on cytochrome P450 enzymes in the Australian asteroid Coscinasterias muricata
Georgiades, E.T.; Danis, B.; Gillan, D.C.; Dubois, P.; Temara, A.; Holdway, D.A. (2006). Effect of crude oil contaminated sediment exposure on cytochrome P450 enzymes in the Australian asteroid Coscinasterias muricata. Chemosphere 65(10): 1869-1877. https://dx.doi.org/10.1016/j.chemosphere.2006.03.071
In: Chemosphere. Elsevier: Oxford. ISSN 0045-6535; e-ISSN 1879-1298, meer
|  |
| Trefwoorden |
Echinodermata [WoRMS]
Marien/Kust |
| Author keywords |
bioindicator; CYP1A; crude oil; echinodermata |
| Auteurs | | Top |
- Georgiades, E.T.
- Danis, B., meer
- Gillan, D.C., meer
|
- Dubois, P., meer
- Temara, A., meer
- Holdway, D.A.
|
|
| Abstract |
Levels of cytochrome P450 enzymes were measured in pyloric caeca microsomes of the asteroid Coscinasterias muricata following exposure to sediment with nominal concentrations of 0, 0.1 or 2 ml crude oil kg−1 (dry weight) and subsequent depuration. No significant differences were observed in total cytochrome P450 levels or cytochrome P418 levels following the exposure period. However after five days of depuration, levels of total P450 in the pyloric caeca of C. muricata exposed to the highest oiled sediment concentration were significantly lower than in specimens exposed to the other treatments. Cytochrome P418 levels were inversely related to total P450 levels following exposure and subsequent depuration. Preliminary results show that levels of CYP1A-like immunopositive protein (CYP1A-like IPP) in exposed asteroids exhibited a concentration response relationship following the exposure period. Variations in CYP1A-like IPP levels observed during the depuration period may be influenced by the sublethal toxicity of hydrocarbons within the crude oil. |
IMIS is ontwikkeld en wordt gehost door het VLIZ.
